Barkley, 49ers hit with potentially season-ending injuries

New York Giants running back Saquon Barkley (26) is carted to the locker room after being injured during the first half of an NFL football game against the Chicago Bears in Chicago, Sunday, Sept. 20, 2020. (AP Photo/Nam Y. Huh)

Denver Broncos wide receiver Jerry Jeudy (10) is helped from the field after being injured during the first half of an NFL football game against the Pittsburgh Steelers, Sunday, Sept. 20, 2020, in Pittsburgh. (AP Photo/Keith Srakocic)

Players gather around an injured person during the first half of an NFL football game between the New York Jets and the San Francisco 49ers at a nearly empty MetLife Stadium, Sunday, Sept. 20, 2020, in East Rutherford, N.J. (AP Photo/Corey Sipkin)

Denver Broncos defensive end Dre'Mont Jones (93) is tended to by team trainers after being injured during the second half of an NFL football game against the Pittsburgh Steelers, Sunday, Sept. 20, 2020, in Pittsburgh. (AP Photo/Keith Srakocic)

Jacksonville Jaguars center Brandon Linder (65) is helped by medial personnel after being injured in the second half of an NFL football game against the Tennessee Titans Sunday, Sept. 20, 2020, in Nashville, Tenn. (AP Photo/Mark Zaleski)

Denver Broncos quarterback Drew Lock (3) walks off the field with a team trainer after being injured during the first half of an NFL football game against the Pittsburgh Steelers in Pittsburgh, Sunday, Sept. 20, 2020. (AP Photo/Don Wright)